Megakaryocytic alterations in thrombocytopenia: A bone marrow aspiration study

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Megakaryocytic alterations in thrombocytopenia: a bone marrow aspiration study.

CONTEXT Dysplastic changes are well documented in myelodysplastic syndromes (MDS). However, they are also observed in non-MDS hematological conditions. AIMS To evaluate the megakaryocytic alterations in the bone marrow aspirations in cases of non-MDS related thrombocytopenia. SETTING AND DESIGN A prospective study of 144 bone marrow aspirates was conducted in the department of pathology, Ka...

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The Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Diagnosis of Bone Marrow Metastases

Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...

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Study of megakaryocytes in bone marrow aspiration smears in patients with thrombocytopenia

Correspondence: Dr. Prabesh Kr. Choudhary, MD Department of Pathology, Nobel Medical College, Biratnagar, Nepal Email: [email protected] Background: Dysplastic changes in megakaryocyte are well-recognized features of myelodysplastic syndrome. However, several studies have shown it’s occurrence in various other disorders. This study was done to understand the various megakaryocytic alterations ...

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Beware of Bone Marrow: Incidental Detection and Primary Diagnosis of Solid Tumours in Bone Marrow Aspiration and Biopsies; A Study of 22 Cases

Background & objective: Introduction: First detection of any solid tumour as metastatic deposits in bone marrow directs clinicians to start searching for the primary tumour. Detection of bone marrow metastasis determines the stage of the malignancy, prognosis, mode of treatment, chemotherapeutic response and follow-up in case of relapse. The aim of the current...

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Leaders Bone marrow aspiration

Bone marrow aspiration biopsies are carried out principally to permit cytological assessment but also for immunophenotypic, cytogenetic, molecular genetic, and other specialised investigations. Often, a trephine biopsy is carried out as part of the same procedure. Bone marrow aspirations should be carried out by trained individuals who are aware of the indications, contraindications, and hazard...

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ژورنال

عنوان ژورنال: Indian Journal of Pathology and Microbiology

سال: 2009

ISSN: 0377-4929

DOI: 10.4103/0377-4929.56132